Advances in Prostate Gland Health: Ancient Remedies and Modern Medical Breakthroughs.

 

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The prostate gland, crucial for male reproductive health, is increasingly becoming a focus for medical research and innovation. With prostate cancer and other prostate-related disorders impacting millions globally, there is significant interest in both ancient remedies and modern advancements. In this article, I dive into the historical treatments for prostate issues and highlights recent breakthroughs in prostate health, offering insights into evolving therapeutic trends.

Ancient Cures and Traditional Approaches

Ancient cultures recognized the significance of the prostate gland and developed various natural remedies to maintain prostate health. Traditional practices, especially in Asian and African societies, emphasized the use of herbal and natural supplements. Some widely known ancient treatments include:

1. Saw Palmetto Extract: Used by Native Americans and later popularized in Europe, saw palmetto is a palm plant whose berries were known to reduce prostate swelling and relieve symptoms of benign prostatic hyperplasia (BPH). Modern studies suggest saw palmetto’s active compounds may inhibit enzymes linked to prostate enlargement.
2. Pollen Extracts: Derived from rye, corn, and timothy grass, pollen extracts were used in traditional Chinese and Japanese medicine to alleviate urinary symptoms associated with BPH. Today, research shows that pollen extracts may have anti-inflammatory properties and reduce symptoms related to prostate conditions.
3. Pygeum Africanum: Extracted from the African cherry tree, Pygeum has been used by African tribes for centuries to treat urinary tract and prostate issues. Modern research supports its role in managing BPH, likely due to anti-inflammatory compounds that improve urine flow and reduce prostate size.
4. Green Tea: Traditional Chinese medicine has long regarded green tea as beneficial for overall health, including prostate well-being. The catechins in green tea have been studied for their antioxidant properties, potentially slowing prostate cancer progression.

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Recent Medical Breakthroughs and Trends

Over the past few decades, medical research on prostate health has led to significant breakthroughs, with novel therapies and diagnostic techniques emerging to enhance treatment outcomes.

1. Precision Medicine and Genetic Testing: Precision medicine is revolutionizing prostate cancer treatment by tailoring therapies to an individual’s genetic profile. Genetic testing now identifies specific mutations, such as BRCA1 and BRCA2, linked to aggressive prostate cancer, allowing for more personalized treatment plans and earlier interventions.
2. Prostate-Specific Membrane Antigen (PSMA) Targeting: PSMA, a protein found on prostate cancer cells, has become a focal point for targeted therapies. Recently approved drugs, like PSMA-targeted radioligand therapy (Lu-177-PSMA), deliver radiation directly to cancer cells while minimizing damage to surrounding tissue. PSMA-based PET scans also allow for earlier and more accurate detection of prostate tumors.
3. Immunotherapy: Immunotherapy, which harnesses the body’s immune system to fight cancer, is increasingly effective in prostate cancer treatment. Sipuleucel-T (Provenge) is an FDA-approved immunotherapy that works by training immune cells to target prostate cancer cells. Although its effectiveness is generally limited to specific stages, ongoing trials aim to enhance its efficacy in broader patient populations.
4. High-Intensity Focused Ultrasound (HIFU): HIFU is a minimally invasive treatment that uses focused ultrasound waves to heat and destroy prostate tissue, offering a non-surgical option for patients with localized prostate cancer. This technique allows for precise targeting of cancerous cells, reducing the risk of side effects like incontinence and impotence.
5. Cryotherapy and Focal Therapies: Cryotherapy, which freezes and destroys cancerous cells, has been refined as a focal therapy to target only specific areas of the prostate. Focal therapies aim to limit the treatment area, thereby preserving more healthy tissue and reducing side effects, making it suitable for men with low to intermediate-risk cancer.
6. Lifestyle and Diet-Based Interventions: Recent studies emphasize the role of diet and lifestyle in prostate health. Diets rich in vegetables, especially cruciferous vegetables, and low in processed meats are associated with reduced prostate cancer risk. Additionally, studies on vitamins such as D and E, along with supplements like lycopene and selenium, show promising results for maintaining prostate health.
7. Artificial Intelligence (AI) in Prostate Cancer Detection: AI-driven algorithms are enhancing early detection by analyzing MRI and biopsy images to identify prostate abnormalities. Machine learning systems provide faster, more accurate diagnoses, allowing for earlier treatment intervention and monitoring of disease progression.

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Integrative Approaches: Combining Ancient Wisdom and Modern Science

Today, there is a growing movement towards integrative medicine that combines ancient remedies with modern advancements. For example, patients might use traditional herbal supplements alongside cutting-edge therapies to mitigate side effects and enhance overall treatment efficacy. Additionally, natural supplements like curcumin (found in turmeric) and resveratrol (found in red grapes) are increasingly studied for their anti-inflammatory and antioxidant properties in cancer prevention and treatment.

The Future of Prostate Health: Toward Personalized and Preventative Care

The trend in prostate health is shifting towards personalized medicine, where genetic, lifestyle, and environmental factors are considered to create tailored treatment approaches. As diagnostic tools and therapeutic options improve, early detection and targeted therapies will likely become the norm, significantly improving survival rates and quality of life for those with prostate conditions.

In summary, the landscape of prostate health treatment is becoming increasingly dynamic, blending ancient practices with groundbreaking innovations. As research continues to uncover the genetic and molecular mechanisms behind prostate diseases, treatments will become even more effective, with a focus on personalized, less invasive options.

Stay healthy my friends….

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What Is the Prostate? What's Normal?

 

Many men aren't sure what their prostate is, what it does, or when to call a doctor if they think they might have a problem. So, information is the best tool you have in dealing with this aspect of men’s health.

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What Does My Prostate Do?

It is a small gland that is part of the male reproductive system. It's supposed to be about the shape and size of a walnut.

It rests below your bladder and in front of your rectum. It surrounds part of the urethra, the tube in your penis that carries pee from your bladder.

The prostate helps make some of the fluid in semen, which carries sperm from your testicles when you ejaculate.

This Gland Can Grow

As you age, your prostate can become larger. It’s a normal part of aging for most men.

By the time you reach age 40, your prostate might have gone from the size of a walnut to the size of an apricot. By the time you reach 60, it might be the size of a lemon.

Because it surrounds part of the urethra, the enlarged prostate can squeeze that tube. This causes problems when you try to pee. Typically, you won’t see these problems until you’re 50 or older, but they can start earlier.

You might hear a doctor or nurse call this condition benign prostatic hyperplasia, or BPH for short. It is not cancerous.

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Who Might Get an Enlarged Prostate?

BPH is common and cannot be prevented. Age and a family history of BPH are two things that increase the chances you might get it. A few stats on that:

• Some 8 out of every 10 men eventually develop an enlarged prostate.
• About 90% of men over the age of 85 will have BPH.
• About 30% of men will find their symptoms bothersome.

Symptoms

If you have trouble starting to urinate or have to go a lot, especially at night, these could be signals that you have an enlarged prostate. Other signs and symptoms include:

• Your bladder doesn’t empty completely after you pee
• You feel the need to go out of the blue with no sensation of build-up
• You may stop and start several times
• You have to strain to get any flow going

It’s important that you see your doctor if you have early symptoms of BPH. Although rare, it can lead to serious problems such as kidney or bladder damage.

A larger prostate doesn’t mean you’ll have more or worse symptoms. It’s different for each person. In fact, some men with very large prostates have few, if any, issues. But your doctor should be aware either way.

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Treatments

How your doctor handles your condition depends on the details of your case -- your age, how much trouble it’s causing, and more. Treatments may include:

Watchful waiting. If you have an enlarged prostate but are not bothered by symptoms, you may be advised merely to get an annual checkup, which might include a variety of tests.

Lifestyle changes. This includes cutting back on how much you drink at night and before bedtime, especially drinks with alcohol or caffeine.

Medicine. Common treatments for BPH are alpha-blockers, which ease BPH symptoms, and what’s called 5-alpha reductase inhibitors, or 5-ARIs, which help shrink the prostate. Many men may take them together.

The FDA now requires labels on the 5-ARIs to include a warning that they may be linked to an increased chance of a serious form of prostate cancer. These medications are dutasteride (Avodart) and finasteride (Propecia and Proscar). The combination pill Jalyn also contains dutasteride as one of its ingredients.

Surgery. Men with severe symptoms who haven't been helped by other treatments might have to turn to surgery. Talk to your doctor about possible risks and outcomes.

 

Prostatitis

This is an infection or inflammation of the prostate; it’s not the same thing as BPH, though some of the symptoms are similar.

It can affect men from their late teens well into old age. Symptoms include:

• Trouble passing urine
• Chills and fever
• Sexual problems

Treatment usually includes antibiotics.

If you have recently had a catheter or other medical instrument put into your urethra, you have a higher chance of getting bacterial prostatitis. Some sexually transmitted diseases, such as chlamydia, may also cause ongoing infection and inflammation.

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Prostate Tests

Your doctor can use a variety of tests to check on the condition of your prostate. A few of them include:

Digital rectal exam: Your doctor puts on a glove and gently inserts one finger into your rectum to check the size and shape of your prostate. They check for things such as size, firmness, and any lumps.

Prostate-specific antigen test: This blood test checks the amount of a protein called PSA that is produced by prostate cells. Higher levels may be a sign of cancer. By themselves, they are not proof you have prostate cancer.

Higher levels could also point to an enlarged prostate or prostatitis. But, levels may be low even with men who have prostate cancer, so discuss the results with your doctor.

Prostate biopsy: Men with high PSA results or other symptoms of cancer may have a tissue sample taken of their prostate to determine whether cancer is present.

Screening for Cancer

Screening for prostate cancer is controversial. You may read different kinds of advice and guidance from various sources. Talk to your doctor about what is best for you.

The American Cancer Society: It says men should talk to their doctors about the benefits, risks, and limits of prostate cancer screening before deciding whether to be tested. This discussion should take place:

• At age 50 for men with an average chance for prostate cancer
• At 45 for men with a higher chance for the condition: this includes African-Americans and men who have a father, brother, or son who has been diagnosed with prostate cancer at 65 or younger
• At age 40 for men who have more than 1 first-degree relative (father, brother, or son) diagnosed with prostate cancer at an early age

The American Urological Association: It recommends that men ages 55 to 69 who are considering screening should talk with their doctor about the risks and benefits of testing and make the decision based on their personal situation and needs.

The group does not suggest screening for:

• Men 39 and younger
• Men who are 40 to 54 and have only an average chance of getting cancer

A routine interval of 2 years or more may be preferred over yearly tests in those men who have decided on screening after talking with their doctor.

Compared with annual screening, it is expected that 2-year intervals give you most of the benefits and reduce false positive results.

Routine PSA screening is not recommended for men older than 70 or for any man who is expected to live only 10 to 15 more years.

The U.S. Preventive Services Task Force: It recommends that men ages 55 to 69 who are considering screening should talk with their doctor about the risks and benefits of testing and make the decision based on their personal situation and needs.

Routine PSA screening is not recommended for men older than 70.

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Written by WebMD Editorial Contributors

Medically Reviewed by Carmelita Swiner, MD on November 18, 2020

Treating an Enlarged Prostate with Diet

The majority of American men will develop a pathologically enlarged prostate gland (also known as benign prostatic hyperplasia, or BPH). The good news, though, is that like many other epidemics of chronic disease plaguing the Western world, it can be prevented and treated with a plant-based diet.

 

Enlarged prostate? Night-time peeing? CURED!

 

The prostate gland surrounds the urethra as it exits the bladder. If the gland gets too big it can constrict the normal flow of urine. Men can be left with a hesitant, weak urine stream, dribbling, irritation, and inadequate emptying of the bladder requiring multiple nightly trips to the bathroom. In the United States, it affects about 50% of men in their 50′s and 80% of men in their 80′s, but as I note in my 3-min. video Some Prostates Are Larger than Others it’s extremely rare in certain populations and diet may be to blame for our BPH epidemic. What if you already have it though?

According to a recent review I profile in my 3-min. video, Prostate Versus Plants, the most notable development in the epidemic of prostate enlargement and lower urinary tract symptoms is the recognition that modifiable lifestyle factors such as diet can substantially influence the progression of the disease. All men should consider eating a prostate-healthy diet that includes legumes (beans, peas, lentils, soy); certain vegetables (like garlic and onions); and certain seeds (flax seeds); and avoids refined grains, eggs, and poultry.

If individual plant foods reduce the risk of prostate enlargement, what about an entire diet composed of plant foods? In my last blog post, Cancer-Proofing Your Body, I showed how a healthy diet can slow down the abnormal growth of prostate cancer cells, but what about the abnormal growth of normal prostate cells?

 

Enlarged prostate? Night-time peeing? CURED!

 

In a similar series of experiments researchers took a bunch of men and put them on a plant-based diet for 2 weeks. Then they dripped the mens’ blood on prostate cells growing in a petri dish and saw, as with the cancer, a significant drop in growth. As I detail in my video Prostate Versus a Plant-Based Diet not only do prostate cell growth rates drop almost immediately upon adopting a healthier diet, but follow-up studies on men eating plant-based diets for up to 28 years straight show that as long as one continues to eat healthy, prostate cell growth rates go down and they stay down.

For more on the health benefits of garlic and onions see:

• New Mineral Absorption Enhancers Found
• Pretty in Pee-nk
• #1 Anticancer Vegetable

More on flax in:

• Breast Cancer Survival and Lignan Intake
• Flax and Fecal Flora
• Just the Flax, Ma’am

And more on the concerns about poultry:

• EPIC Findings on Lymphoma
• Chicken Dioxins, Viruses, or Antibiotics?
• Poultry and Penis Cancer
• Poultry Exposure and Neurological Disease
• 
  

Enlarged prostate? Night-time peeing? CURED!

 

 

Written By Michael Greger M.D. FACLM on February 5, 2013